Carbopol® 934P NF Polymer

Applicable synonyms for Carbopol^® 934P NF Polymer: carbomer, carboxypolymethylene 

Polymerization/Residual solvent: Benzene

Key features: 

• Thickener/rheology modifier

Additional features:

• Extended release agent
• Suspension and emulsion stabilizer
• Bioadhesive agent

Recommended for use in the following dosage forms:

• Semisolids & gels
• Solutions & suspensions
• Extended release oral solid doses

Recommended for use in the following markets / routes of administration:

• Oral drug delivery
• Topical drug delivery

Carbopol® 934P NF polymer meets the limits cited in the current edition of the following monographs: 

• United States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer 934P 
• Japanese Pharmaceutical Excipients (JPE) Monograph for Carboxyvinyl Polymer

Usage levels: 

• Oral solutions & suspensions: 0.2-1 wt%
• Topical: 0.5-3 wt%

Note on toxicity testing:

The toxicity of carbomers has been summarized by the Cosmetic Ingredient Review Expert Panel in their assessment of the safety of the carbomers for cosmetic ingredients. This assessment and subsequent toxicology testing have demonstrated a low toxicity and irritation potential. Lubrizol has supporting data for dermal, ocular, and oral toxicology testing for Carbopol 934P NF polymer. Bulletin 2 provides a summary of all toxicology studies for Lubrizol’s pharmaceutical grade polymers.

Additionally, Lubrizol has filed a Type V DMF with FDA. A letter of authorization (LOA) can be issued for FDA drug applications.