New Data Unveils Argireline® Amplified Peptide's Ability to Extend Anti-Wrinkle Effects of Cosmetic Injections

CLEVELAND, Ohio –Lubrizol, a global specialty chemical leader, is excited to announce the results of a groundbreaking clinical study demonstrating that the combination of Argireline® Amplified peptide and Botulinum toxin type-A (BTA) injections can keep wrinkles at bay for nearly 8 weeks longer than BTA alone. This naturally derived peptide not only enhances but also prolongs the anti-aging effects of cosmetic injections, providing a more enduring solution for wrinkle reduction.

Evolution of the globally renowned Argireline® peptide and designed addressing the principles of Green Chemistry, Argireline® Amplified peptide boasts superior in vitro activity and added muscle relaxation effects as compared to the original Argireline® peptide. Initially utilized in topical treatments as a non-invasive alternative to reduce facial muscle activity, Argireline® Amplified peptide has now been clinically proven to significantly extend the effects of BTA injections when used in combination.

In the recent study, 45 Caucasian volunteers, both male and female, aged between 35 and 60, received 50 UI Botulinum toxin type A injections in the crow’s feet, frown lines, and forehead areas. They also applied a cream containing 5% Argireline® Amplified peptide solution or a placebo cream to their entire face twice daily for 4 months. Researchers utilized 2D and 3D facial imaging to monitor changes in wrinkle visibility, skin roughness, and wrinkle length in areas such as crow’s feet, frown lines, and the forehead.

Results showed that after 1, 3, and 4 months, participants who received the active peptide combination treatment exhibited significantly fewer wrinkles compared to those who received BTA and a placebo. This combination treatment extended the wrinkle-free period by almost 8 weeks longer than BTA alone.

The synergy between BTA and Argireline® Amplified peptide meets the growing demand for effective, longer-lasting dermo-aesthetic solutions, allowing consumers to make fewer trips to the clinic and spend more time enjoying the benefits of smooth, youthful skin.

For more information about Argireline® Amplified peptide, please visit Lubrizol.com.

About The Lubrizol Corporation

The Lubrizol Corporation, a Berkshire Hathaway company, is a science-based company whose specialty chemistry delivers sustainable solutions to advance mobility, improve well-being and enhance modern life. Every day, the innovators of Lubrizol strive to create extraordinary value for customers at the intersection of science, market needs and business success, driving discovery and creating breakthrough solutions that enhance life and make the world work better. Founded in 1928, Lubrizol has global reach and local presence, with more than 100 manufacturing facilities, sales and technical offices and more than 7,500 employees around the world. For more information, visit www.Lubrizol.com.

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